产品货号：
Z20764
中文名称：
MTA2抗体
英文名称：
Anti-MTA2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MTA2 Antibody |
| 指标别名 | Metastasis associated 1 like 1;MTA1L1 protein;MTA1L1;MTA2;PID |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF,IHC |
| 基因名称 | MTA2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PID antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PID.The immunogen is located within the last 50 amino acids of PID. |
| 计算分子量 | 75kDa |
| 成分 | PID Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PID Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 pathway,including Chk2,p53R2,p53AIP1,Noxa,PIDD,and PID/MTA2,were recently discovered.The transcriptional activity of p53 is modulated by protein stability and acetylation.PID/MTA2,also termed MTA1-L1,was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex.PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53.Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis.PID/MTA2 is ubiquitously expressed in human tissues. |
| Uniprot ID | O94776 |
| 基因名全称 | Metastasis associated 1 family,member 2 |
| 蛋白名全称 | Metastasis associated 1 family,member 2 |
| 推荐稀释比 | PID antibody can be used for detection of PID by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL and Immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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